Recombinase Polymerase Amplification (RPA) - the isothermal DNA/RNA amplification that really works.

Explore the latest publications below to see how scientists are using our rapid, robust and reliable technology to replace PCR in areas as diverse as infectious diseases, microfluidics, animal diagnostics and plant pathogens.

Quantify pathogens in water.

Use RPA with on-chip, chemiluminescence microarray platforms.

Play video

Multiplex. At 37˚C.

Detect multiple potential biowarfare agents at the same time.
 

Play video

Superb sensitivity. No thermocycler.

Detect as little as 14pg/µl of purified plant virus RNA.
 

Play video

Our products

TwistAmp® Exo

TwistAmp® exo

Real-time fluorescent DNA amplification made possible with a TwistAmp® exo kit. Recommended for users ...

More info
TwistAmp® exo RT

TwistAmp® exo RT

One step real-time fluorescent RNA amplification made possible with a TwistAmp® exo RT kit. ...

More info
TwistAmp® nfo (Improved Formulation)

TwistAmp® nfo

DNA amplification for lateral flow detection made possible with a TwistAmp® nfo kit. Designed ...

More info
TwistAmp® fpg

TwistAmp® fpg

Alternative real-time, and end-point fluorescent DNA detection made possible with a TwistAmp® fpg kit. ...

More info
TwiatAmp Liquid Basic

TwistAmp® Liquid Basic

DNA amplification in a flexible liquid format. Contains all the enzymes and reagents necessary for ...

More info
TwiatAmp Liquid BasicRT

TwistAmp® Liquid Basic RT

One step RNA amplification in a flexible liquid format Recommended for those that want to ...

More info
TwiatAmp Liquid Exo

TwistAmp® Liquid exo

Real-time fluorescent DNA amplification in a flexible liquid format. Recommended for users who want to ...

More info
TwistAmp® Liquid exo RT

TwistAmp® Liquid exo RT

One step real-time fluorescent RNA amplification in a flexible liquid format. Recommended for users who ...

More info

Latest news

PRESS RELEASE - TwistDx offer isothermal alternative to PCR

“The ever growing number of peer-reviewed publications using our technology demonstrates the benefits of RPA as a genuine alternative to traditional PCR techniques."

Read more

About us

TwistDx Inc. was founded in 1999 by molecular biologist and protein biochemist, Dr Niall Armes, together with Dr Derek Stemple and Dr Nagesh Mahanthappa with its headquarters in Cambridge Massachusetts, USA. TwistDx Limited was formed in 2002, its operational facilities are in Cambridge, UK.

Read More
Information Background

RPA. It really works.