TwistDx™ blog

Bringing you the latest ideas, opinions and news from the RPA community.

  • Detection: a multitude of options

    Many RPA users will want to be able to detect that DNA amplification has occurred and monitor this over the course of a reaction. When we first developed the technology, we needed to create RPA-specific methods for achieving this. Resolving the product of your reaction on an agarose or polyacrylamide gel is the most common method for post-PCR detection, yet this is out of the question for high throughput activities or point-of-care applications, and undermines our aim of simplifying the equipment and protocols of molecular diagnostic techniques. A […]

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  • Lyophilised Or Liquid?

    One of our key aims at TwistDx is to make the RPA workflow as simple as possible, eliminating the pipetting of multiple reagents and freeing the user to focus on their research. As a result, we now offer RPA kits in two formats – lyophilised pellets and a liquid – each with unique strengths, suitable for different applications and requirements. Lyophilised – no expertise neededRPA has a number of advantages over PCR. The isothermal technique dispenses with thermocycling instruments and offers rapid results within five to 20 minutes, making […]

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  • TwistDx: A history of science, serendipity and success

    The curious aspect of scientific research is that you never know where it will lead you. TwistDx started 18 years ago – back then it was ASM Scientific – and we could not have predicted that we would find ourselves pioneering the use of RPA in 2017. A mix of good ideas, circumstances, and trial and error have led us to where we are today, and will no doubt continue to accompany our future success. Aiming in a different directionNot everyone knows that TwistDx […]

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  • Who are the innovators pioneering the future of RPA?

    The future is difficult to predict, but, as CEO, I am often asked about a vision for the years ahead and the growing role RPA can play. There is already much evidence to suggest a broad uptake of the technology, with over 200 publications, and I’m delighted to see the growing adoption of RPA as customers see the benefits over competing technologies, thanks to its robustness, sensitivity and speed. In truth, the future of RPA belongs to the scientists, engineers and entrepreneurs who are exploring its […]

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